Variation in Restarting Antithrombotic Drugs at Hospital Discharge After Intracerebral Hemorrhage

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Variation in restarting antithrombotic drugs at hospital discharge after intracerebral hemorrhage.

BACKGROUND AND PURPOSE Whether intracerebral hemorrhage (ICH) survivors should restart antithrombotic drugs is unknown. We analyzed the frequency of restarting antithrombotic drugs in ICH survivors who had taken prophylactic antithrombotic drugs in atrial fibrillation or after thromboembolic disease in 5 cohorts and explored factors associated with doing so. METHODS We compared the characteri...

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Neuroinflammation after intracerebral hemorrhage

Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which no specific treatment has been established yet. Although preclinical models of ICH have substantial methodological limitations, important insight into the pathophysiology has been gained. Mounting evidence suggests an important contribution of inflammatory mechanisms to brain damage and potential repair...

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Restarting Anticoagulant Therapy After Intracranial Hemorrhage

Atrial fibrillation increases the risk of stroke 3to 5-fold and is implicated in about 15% of all strokes every year. Anticoagulation therapy has been proven to be efficacious in reducing incident stroke and systemic embolism in patients with atrial fibrillation and mechanical heart valves. However, the benefits of anticoagulation must be carefully weighed against the increased risk of intracra...

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Restarting oral anticoagulation after intracranial hemorrhage.

To the Editor: In their recent article, Eckman and colleagues highlight a difficult clinical decision: whether it is safe to restart anticoagulation for atrial fibrillation after intracerebral hemorrhage, and they cite the lack of published data addressing the issue.1 We agree that decisions must be made based on the relative risks versus benefits in individual patients, which will vary dependi...

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Antithrombotic medications and the etiology of intracerebral hemorrhage: MUCH-Italy.

OBJECTIVE To test the hypothesis that the effect of antithrombotic medications on the risk of intracerebral hemorrhage (ICH) varies according to the location of the hematoma. METHODS Consecutive patients with ICH were enrolled as part of the Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy). Multivariable logistic regression models served to examine whether risk factors for ICH a...

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ژورنال

عنوان ژورنال: Stroke

سال: 2014

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.114.006202